Eniyan Ros1 Fusion Litani tuka
Orukọ ọja
HWTS-TM009-Eniyan Ros1 Fusion Live Iwari Iwari Iduroṣinṣin Kit (FURRORCECCECECEC)
Iwe-ẹri
CE
Onimọraciology
Ros1 jẹ Trosie Tyrosie ti Insulini ti Ile-iṣẹ Igbasilẹ Insulini. Ros1 Lilo Gene ti jẹrisi gẹgẹbi miiran pataki miiran ti ko ṣe pataki ẹdọforo wa fun ẹbun. Gẹgẹbi aṣoju ti Subtype iyalẹnu alailẹgbẹ tuntun, iṣẹlẹ ti Ros1 Ifilelẹ Ninu NSCLC O fẹrẹ to 2% Ros1 Pataki Awọn Ede Gengan ni awọn exons pẹlu CD74, Ezr, SLC34a2, ati SDC4, yoo tẹsiwaju lati muu Agbegbe Ros1 Trosese kan. Ti ko darukọ Ros1 kan ti o ni aiṣedede lati mu awọn ipa-ọna awọn ipa-ọna fifa mọ silẹ bi ras / Spyk, ati Jak3 / Orisun ati Akàn nfa akàn nfa alakan. Laarin awọn iyipada Ros1, CD74-Ros1 fun bii 152%, awọn iroyin Ezr fun awọn akọọlẹ 15%, awọn iroyin SLC344A2, ati awọn iroyin SDC4 fun bii 7%. Awọn ijinlẹ ti fihan pe aaye ATP-tintering ti Abala àkọsílẹ ti Ros1 Kinase ati ATP-tintenine kekere ti o to 77%, nitorinaa alk trosine kilisiti chizatinab ati bẹbẹ lọ ni ipa alumoni ti o han gbangba Ni itọju ti NSCLC pẹlu iyipada foosion ti Ros1. Nitorinaa, iwari ti Ros1 Fusions jẹ ile-aye ati ipilẹ fun ṣiṣe itọsọna lilo awọn oogun crizotinib.
Ikanni
| Fa | IKILỌ NIPA 1, 2, 3 ati 4 |
| Vic (hex) | IKILỌ NIPA 4 |
Awọn ohun elo imọ-ẹrọ
| Ibi ipamọ | ≤-18 ℃ |
| Oju aye | Oṣu Kẹsan 9 |
| Iru apẹrẹ | paraffin-saffind ti a samúró tabi awọn ayẹwo ti a ge wẹwẹ |
| CV | <5.0% |
| Ct | ≤3 |
| Lto | Ohun elo yii le rii awọn iyipada to dara julọ bi kekere bi awọn adakọ 20. |
| Awọn ohun elo ti o wulo: | Lo awọn biosystems 7500 awọn eto PC-akoko akoko-akokoLoo biositystems 7500 iyara awọn eto PC-akoko Slan ®-96p Awọn ọna PCR Awọn ọna Awọn eto Purtudio ™ 5 Awọn eto PC-akoko gidi Ẹrọ Percyclercler®480 Eto PRC Linegene 9600 Plut eto iṣawari PRR Ma-6000 Gigun kẹkẹ-nla Eto PFX96 Akoko PRC Biokad CFX Opus 96 Eto PRC |
Iṣẹ sisan
Awọn iṣeduro isediwon isediwon ti a ṣe iṣeduro: RNEY FFPE ohun elo (73504) Lati Ìgágé, Paraffin ifibọ apakan (DP439) lati Tiangen isecle (Beijing) Co., Ltd.
