● Àrùn ikọ́ ẹ̀gbẹ Mycobacterium
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Mycobacterium Tuberculosis Nucleic Acid ati Rifampicin (RIF) ， Isoniazid Resistance (INH)
Ọja yii dara fun wiwa didara ti Mycobacterium iko DNA ninu awọn ayẹwo sputum eniyan ni vitro, bakanna bi iyipada homozygous ni agbegbe 507-533 amino acid codon (81bp, agbegbe ti npinnu resistance rifampicin) ti jiini rpoB ti o fa ikọ-ara Mycobacterium rifampicin resistance.
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Mycobacterium Tuberculosis Isoniazid Resistance Mutation
Ohun elo yii dara fun wiwa didara ti awọn aaye iyipada akọkọ ninu awọn ayẹwo sputum eniyan ti a gba lati ọdọ awọn alaisan Tubercle bacillus rere ti o yorisi ikọlu mycobacterium isoniazid resistance: Agbegbe olupolowo InhA -15C>T, -8T>A, -8T>C;AhpC agbegbe olupolowo -12C>T, -6G>A;Iyipada homozygous ti KatG 315 codon 315G>A, 315G>C.
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Mycobacterium Tuberculosis Resistance Rifampicin
Ohun elo yii dara fun wiwa agbara ti iyipada homozygous ni agbegbe 507-533 amino acid codon ti jiini rpoB ti o fa ikọlu Mycobacterium rifampicin resistance.
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Mycobacterium Tuberculosis Nucleic Acid ati Rifampicin Resistance
Ohun elo yii dara fun wiwa ti agbara ti Mycobacterium iko DNA ninu awọn ayẹwo sputum eniyan ni vitro, bakanna bi iyipada homozygous ni agbegbe 507-533 amino acid codon ti jiini rpoB ti o fa idiwọ Mycobacterium tuberculosis rifampicin.
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Mycobacterium Tuberculosis INH Resistance
Ohun elo yii ni a lo lati ṣe awari ni iwọn-iyipada jiini ti 315th amino acid ti jiini katG (K315G>C) ati iyipada pupọ ti agbegbe olupolowo ti Jiini InhA (- 15 C>T).
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Mycobacterium Tuberculosis DNA
O dara fun wiwa didara ti Mycobacterium iko DNA ninu awọn ayẹwo sputum ile-iwosan eniyan, ati pe o dara fun iwadii iranlọwọ iranlọwọ ti ikolu Mycobacterium iko.
