Apapọ Awọn ọlọjẹ atẹgun
Orukọ ọja
HWTS-RT158A Awọn Eegun Ẹmi Apopọ Ohun elo Iwari (Fluorescence PCR)
Iwe-ẹri
CE
Arun-arun
Arun Iwoye Corona 2019, tọka si bi'COVID 19', tọka si pneumonia ti o ṣẹlẹ nipasẹ ikolu 2019-nCoV. 2019-nCoV jẹ coronavirus ti o jẹ ti iwin β. COVID-19 jẹ arun ajakalẹ-arun ti atẹgun nla, ati pe olugbe ni ifaragba gbogbogbo. Ni lọwọlọwọ, orisun ti akoran jẹ pataki awọn alaisan ti o ni akoran nipasẹ 2019-nCoV, ati pe awọn eniyan ti o ni akoran asymptomatic le tun di orisun ti akoran. Da lori iwadii ajakale-arun lọwọlọwọ, akoko isubu jẹ awọn ọjọ 1-14, pupọ julọ awọn ọjọ 3-7. Iba, Ikọaláìdúró gbigbẹ ati rirẹ jẹ awọn ifarahan akọkọ. Awọn alaisan diẹ ni awọn aami aiṣan bii isunmi imu, imu imu, ọfun ọfun, myalgia ati gbuuru, ati bẹbẹ lọ.
Aarun ajakalẹ-arun, ti a mọ ni “aisan”, jẹ arun ajakalẹ-arun atẹgun ti o fa nipasẹ ọlọjẹ aarun ayọkẹlẹ. O ti wa ni gíga àkóràn. O ti wa ni o kun tan nipasẹ iwúkọẹjẹ ati sneezing. O maa n jade ni orisun omi ati igba otutu. Awọn ọlọjẹ aarun ayọkẹlẹ ti pin si aarun ayọkẹlẹ A (IFV A), aarun ayọkẹlẹ B (IFV B), ati aarun ayọkẹlẹ C (IFV C) awọn oriṣi mẹta, gbogbo wọn jẹ ti ọlọjẹ alalepo, ti o fa arun eniyan ni pataki fun awọn ọlọjẹ A ati B, o jẹ ọlọjẹ RNA kan ti o ni okun, ti o pin si. Kokoro aarun ayọkẹlẹ jẹ akoran ti atẹgun nla, pẹlu H1N1, H3N2 ati awọn ẹya-ara miiran, eyiti o ni itara si iyipada ati ibesile agbaye. "Iyipada" ntokasi si iyipada ti aarun ayọkẹlẹ A kokoro, Abajade ni ifarahan ti kokoro tuntun "subtype". Awọn ọlọjẹ aarun ayọkẹlẹ B ti pin si awọn idile meji, Yamagata ati Victoria. Kokoro aarun ayọkẹlẹ B nikan ni fiseete antigenic, ati pe o yago fun eto iwo-kakiri ati imukuro eto ajẹsara eniyan nipasẹ iyipada rẹ. Sibẹsibẹ, iyara itankalẹ ti ọlọjẹ aarun ayọkẹlẹ B jẹ o lọra ju ti ọlọjẹ aarun ayọkẹlẹ eniyan A. Kokoro aarun ayọkẹlẹ B tun le fa awọn akoran atẹgun eniyan ati ja si awọn ajakale-arun.
Kokoro syncytial ti atẹgun (RSV) jẹ ọlọjẹ RNA kan, ti o jẹ ti idile paramyxoviridae. O ti gbejade nipasẹ awọn isunmi afẹfẹ ati isunmọ isunmọ ati pe o jẹ pathogen akọkọ ti ikolu ti atẹgun atẹgun ninu awọn ọmọde. Awọn ọmọde ti o ni RSV le ni idagbasoke bronchiolitis ti o lagbara ati pneumonia, eyiti o ni ibatan si ikọ-fèé ninu awọn ọmọde. Awọn ọmọ ikoko ni awọn aami aiṣan ti o lagbara, pẹlu iba giga, rhinitis, pharyngitis ati laryngitis, ati lẹhinna bronchiolitis ati pneumonia. Diẹ ninu awọn ọmọde aisan le ni idiju pẹlu otitis media, pleurisy ati myocarditis, bbl
ikanni
| FAM | SARS-CoV-2 |
| VIC(HEX) | RSV |
| CY5 | IFV A |
| ROX | IFV B |
| Kúsari 705 | Iṣakoso ti abẹnu |
Imọ paramita
| Ibi ipamọ | -18 ℃ |
| Selifu-aye | 12 osu |
| Apeere Iru | Oropharyngeal swab |
| Ct | ≤38 |
| LoD | 2019-nCoV: 300Awọn ẹda / milimita Kokoro aarun ayọkẹlẹ A / Kokoro aarun ayọkẹlẹ B / Kokoro syncytial ti atẹgun: 500 Awọn ẹda/mL |
| Ni pato | a) Awọn abajade ifaseyin agbekọja fihan pe ko si ifaseyin agbelebu laarin ohun elo ati coronavirus eniyan SARSr-CoV, MERSr-CoV, HCoV-OC43, HCoV-229E, HCoV-HKU1, HCoV-NL63, ọlọjẹ parainfluenza iru 1, 2, 3, rhinovirus A, B,virus eniyan, chulamyvirus A, B, C. enterovirus A, B, C, D, kokoro epstein-barr, kokoro measles, kokoro cytomegalo eniyan, rotavirus, norovirus, parotitis virus, virus varicella-zoster, legionella, bordetella pertussis, haemophilus influenzae, staphylococcus aureus, streptococcus, pneumonia, streptococcus, pneumonia. pneumoniae, mycobacterium tuberculosis, ẹfin aspergillus, candida albicans, candida glabrata, pneumocystis jiroveci ati cryptococcus ọmọ ikoko ati eda eniyan genomic nucleic acid. b) Agbara kikọlu: yan mucin (60mg / mL), 10% (v / v) ti ẹjẹ ati phenylephrine (2mg / mL), oxymetazoline (2mg / mL), iṣuu soda kiloraidi (pẹlu awọn olutọju) (20mg / mL), beclomethasone (20mg / mL), 20mgolimde, dexamnisethasone. (20μg/mL), triamcinolone acetonide (2mg/mL), budesonide (2mg/mL), mometasone (2mg/mL), fluticasone (2mg/mL), histamine hydrochloride (5mg/mL), alpha interferon (800IU/ml), zanamivir (20mg/ml0), ogidimivir (20mg/ml0), opim ribavirin (60ng/ml), peramivir (1mg/mL), lopinavir (500mg/mL), ritonavir (60mg/mL), mupirocin (20mg/mL), azithromycin (1mg/mL), ceftriaxone (40μg/ml), meropenem (200mg/mL), toflocin (200mg/mL), toflocin (0.6mg / mL) fun idanwo kikọlu, ati awọn abajade fihan pe awọn nkan kikọlu pẹlu awọn ifọkansi ti a mẹnuba loke ko ni idahun kikọlu si awọn abajade idanwo ti awọn ọlọjẹ. |
| Awọn ohun elo ti o wulo | BioRad CFX96 Real-Time PCR System Rotor-Gene Q 5plex HRM Platform gidi-akoko PCR System |
